Putting their own twist on robots that amble through complicated landscapes, the Stanford Student Robotics club's Extreme Mobility team has developed a four-legged robot that is not only capable of performing acrobatic tricks and traversing challenging terrain but is also designed with reproducibility in mind. Anyone who wants their own version of the robot, dubbed Stanford Doggo, can consult comprehensive plans, code and a supply list that the students have made freely available online.
* This article was originally published here
Monday 20 May 2019
Pool chemical injuries led to ~13,500 ED visits in 2015-2017
(HealthDay)—Pool chemical injuries led to an estimated 13,508 U.S. emergency department visits during 2015 to 2017, and about one-third of these injuries occurred in children, according to research published in the May 17 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
* This article was originally published here
* This article was originally published here
Researchers discover placental stem cells that can regenerate heart after heart attack
Researchers at the Icahn School of Medicine at Mount Sinai have demonstrated that stem cells derived from the placenta known as Cdx2 cells can regenerate healthy heart cells after heart attacks in animal models. The findings, published in the May 20 issue of Proceedings of the National Academy of Sciences (PNAS), may represent a novel treatment for regenerating the heart and other organs.
* This article was originally published here
* This article was originally published here
Circadian mechanism may not be driver behind compound linked to obesity and diabetes
SR9009 is a compound that can lead to a wide range of health benefits in animals, including reduced risk of obesity and type 2 diabetes. Until now, researchers—and companies that sell the compound for human use in the form of a nutraceutical—have attributed the effects to SR9009's role in altering the body's circadian clock, specifically its work through proteins called REV-ERBS that link metabolism and circadian rhythm. However, in a first-of-its-kind study from Penn Medicine, published today in PNAS, researchers found that SR9009 can effect cell growth and metabolic function without the involvement of REV-ERBs.
* This article was originally published here
* This article was originally published here
Studies: Benralizumab not effective reducing exacerbations in moderate to very severe COPD
More than 15.3 million people in the U.S. suffer from chronic obstructive pulmonary disease (COPD), which is the third leading cause of death in this country, according to the American Lung Association. Patients often experience potentially life-threatening exacerbations, which can include days-long flare-ups of symptoms including shortness of breath that occur when the airways narrow from muscle tightness, swelling and mucus.
* This article was originally published here
* This article was originally published here
Key drug target shown assembling in real-time
Over one-third of all FDA-approved drugs act on a specific family of proteins: G-protein coupled receptors (GPCRs). Drugs to treat high blood pressure, asthma, cancer, diabetes and myriad other conditions target GPCRs throughout the body—but a recent study shows what happens next. In results published in Cell, researchers outline the timeline of events, including precisely when and how different parts of a GPCR interacts with its G protein signaling partners. The findings provide new insights into the fundamental mechanisms of drug-induced signaling in cells, including ways to identify the most critical portions of GPCRs for targeting development of novel therapeutics.
* This article was originally published here
* This article was originally published here
Pyrrolizidine alkaloid levels in dried and deep-frozen spices and herbs too high
The German Federal Institute for Risk Assessment (BfR) deals regularly with the contamination of food with 1,2-unsaturated PA. It has already published opinions on the occurrence of 1,2-unsaturated PA in herbal teas, tea and honey, as well as a salad mixture contaminated with ragwort and food supplements (FS). The BfR has now made a health assessment of levels of 1,2-unsaturated PA determined by the monitoring authorities of the federal states in samples of various dried and deep-frozen herbs and spices.
* This article was originally published here
* This article was originally published here
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